As summer draws to a close, the highly transmissible delta variant of SARS-CoV-2 now prevalent in the United States will raise questions from how to get back to work safely to protecting children in schools.

For many people, summer travel plans are also in the balance.

On Tuesday, the Centers for Disease Control and Prevention changed their guidelines for fully vaccinated individuals, advising them to wear masks in locations with high or significant indoor transmission rates. The counties that meet these criteria make up about two-thirds of the US population, according to a CNBC analysis of the agency’s data.

“We are dealing with a different virus now,” said Dr. Anthony Fauci, Senior Medical Advisor to the White House, in an interview with NPR on Tuesday about the Delta variant.

So is traveling safe at all? The answer depends entirely on your individual circumstances, including your risk profile and tolerance, says Dr. Ashley Lipps, assistant professor in the Infectious Diseases Division at Ohio State University’s Wexner Medical Center, told CNBC Make It.

Here are some questions you may have as you approach summer travel plans:

Can I travel if I am vaccinated?

No trip is completely safe and how safe it is depends on individual circumstances.

But the best thing you can do when planning a trip is to make sure that everyone in your tour party who is eligible is fully vaccinated, including all adults, says Lipps. The CDC recommends postponing the trip until you are fully vaccinated.

The rules for unvaccinated people who have to travel are strict: the CDC says that unvaccinated people should be tested one to three days before traveling and again three to five days after returning, plus seven days of quarantine after they return home.

Both in airplanes, buses, trains and other public transport, as well as in transport hubs such as airports and train stations, both vaccinated and unvaccinated persons must wear masks.

Everyone should monitor themselves for Covid symptoms.

Can I bring my young children with me?

Traveling is tricky for families with young children because there are no vaccinations for children under 12 says.

You can also take steps to minimize your exposure to other people, such as:

But Kullar says it is best for families with young children to “wait for this rise to plateau” in order to travel.

Is it safe to fly

Airplanes are inherently a bit riskier because you will be inside and around a lot of other people whose vaccination status you may not know. Make sure you are fully vaccinated before getting on a plane.

Because Delta is more transmissible than other variants, “there is a higher likelihood, especially in indoor airport environments, of putting you at risk and potentially transmitting and spreading you,” says Kullar.

Anyone who wears masks that are required by federal regulations on public transport can reduce the risk of transmission, says Lipps. “If you take the precautions outlined, you can certainly reduce your chance [of infection],” She says.

Kullar says that while masking is mandatory and usually enforced by flight attendants on board the aircraft, you should also be careful at the airport where it is full and wearing masks may not be closely monitored by staff.

“The airport is probably the riskiest,” says Kullar.

According to the CDC, short road trips with members of your household or those who are fully vaccinated with just a few stops are a safer choice.

How do I know how bad Covid is at a destination?

The bottom line is that no goal is risk-free.

“Covid is just widespread everywhere, so there is some risk whether you are in a high-transmission area or a lower-transmission area,” says Lipps.

Knowing the transmission rate at your destination is just one factor that can help you weigh the overall risk to your trip, says Lipps. For example, if you go to a state that the CDC has classified as high or significant transmission, you must wear masks in public indoor spaces whether or not you are vaccinated. In some places, mask requirements now apply.

The CDC has a map that shows you the degree of transmission of the municipality by district. You can also check the state or local Department of Health’s website for specific information about your travel destination.

Also, think about the people you travel with and how their individual risk factors play a role in your decision, says Lipps.

“If you are planning to travel somewhere with very high transmission rates and you have either unvaccinated children or adults who may be immunocompromised or otherwise at high risk, avoiding these types of travel or going anywhere can help to travel where there may be less community broadcast, “she says.

The CDC suggests that you read their travel advice by destination before going abroad.

What about travel outside the country?

Certain countries don’t have as much access to Covid vaccines, “so you may be traveling to places where far fewer people are vaccinated than here in the United States,” says Lipps.

And “in most countries other than the US, the delta is just as worrying, if not more so in some Asian countries,” says Kullar. “I would postpone international travel until we are out of the thicket.”

In addition, rules and regulations change as situations change around the world.

On Wednesday, the UK announced that US and EU travelers no longer need to be quarantined upon arrival in England or Scotland. And Canada will allow fully vaccinated Americans to enter the country starting August 9, for the first time since March 2020.

“You have to be careful when traveling internationally, because changing travel restrictions can result that we cannot yet predict at this point in time,” says Lipps.

Testing requirements, stay at home orders, and quarantine requirements also vary from location to location.

Take the Caribbean islands for example: Bermuda requires unvaccinated visitors to be quarantined for 14 days on arrival. Vaccinated people must also be quarantined in Bermuda until they get a negative PCR test. But in the Bahamas, fully vaccinated people do not need to be tested or quarantined to enter the country.

Another thing to keep in mind when leaving the country: The CDC requires all passengers entering the US to have a negative Covid test result (or proof that you have recovered from Covid) before boarding a flight into the United States Climb USA

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